Mono Propylene Glycol (MPG) (USP Grade)
Mono Propylene Glycol (MPG), USP Grade, is a high-purity, colorless, nearly odorless, and tasteless liquid that conforms to the standards of the United States Pharmacopeia (USP). It is widely used in food, pharmaceutical, cosmetic, and personal care products as a solvent, humectant, and stabilizer.
Propylene Glycol (USP Grade) is a colorless, viscous and odorless liquid. It is highly hygroscopic and miscible in all ratios with water, alcohols, esters, ketones and amines.
It has limited miscibility with halogenated hydrocarbons and is not miscible with aliphatic hydrocarbons. Excellent humectant, Solvent, Carrier, Natural preservative effects, wetting agent, lubricant, Freezing point depressant.
CAS Number: 57-55-6
Chemical Name: Mono Propylene Glycol (MPG)
Other Names: Propylene Glycol, 1,2-Propanediol
Chemical Formula: C₃H₈O₂
Molecular Weight: 76.09 g/mol
Purity (USP Grade): ≥ 99.5%
Appearance: Clear, colorless, viscous liquid
Odor: Faintly sweet or odorless
Solubility: Fully miscible with water, alcohols, and most organic solvents
Boiling Point: ~188.2°C (370.8°F)
Melting Point: ~–59°C
Density: ~1.036 g/cm³ at 20°C
Flash Point: 39°C (closed cup)
pH (1% solution): ~2.4
USP Grade Meaning:
USP-grade MPG meets stringent purity and safety standards defined by the United States Pharmacopeia, making it suitable for:
- Human ingestion (in regulated quantities)
- Pharmaceutical formulations
- Food and beverage processing
Application in areas:
- Pharmaceuticals & Personal Care
- Excipient, solvent, and carrier in oral, topical, and injectable medications
- Found in creams, gels, lotions, and ointments
- Moisturizer in toothpaste, shaving creams, and deodorants
- Food Industry (E1520)
- Used as a food additive, solvent, and carrier for flavors and colors
- Acts as a humectant to retain moisture in processed foods
- E-Liquids & Inhalation Products
- Key ingredient in vape juice (e-cigarettes)
- Carrier in aerosolized medications and inhalation therapies
- Animal Feed
- Used as an energy source and stabilizer in livestock nutrition
Safety & Handling:
- GHS Classification: Generally considered non-hazardous in USP applications
- Toxicity: Low; very low oral toxicity to humans and animals
- LD50 (Oral, rat): ~20,000 mg/kg
PPE Requirements:
- Nitrile gloves
- Safety goggles
- Protective clothing if handling bulk or heated product
Regulatory Compliance:
- USP / FCC / Food Grade
- Kosher / Halal (varies by supplier)
- Compliant with FDA CFR 21 (for food and pharma uses)
Storage Guidelines:
- Store in cool, dry, well-ventilated area
- Keep containers tightly closed
- Hygroscopic – protect from moisture contamination
Packaging: Bulk, Drum, IBC