Polyethylene Glycol 1000
CAS Number: 25322-68-3
Chemical Name: Polyethylene Glycol 1000
Other Names: PEG 1000, Macrogol 1000
Chemical Formula: H(OCH₂CH₂)nOH
Molecular Weight: ~950–1050 g/mol
Average Ethylene Oxide Units (n): ~20–23
Appearance: White to off-white waxy solid (flakes or pellets)
Odor: Odorless
Taste: Tasteless
Solubility: Freely soluble in water, alcohol, and acetone; insoluble in hydrocarbons
Boiling Point: Decomposes before boiling
Melting Point: Approx. 37–40 °C
pH (5% aqueous solution): ~5.0–7.0
Application in areas:
- Pharmaceutical & Personal Care
- Base for ointments, creams, lotions, and suppositories
- Acts as a solubilizer, humectant, and thickener
- Non-irritating, non-sensitizing—ideal for topical and internal use
- Industrial and Technical
- Used as an antistatic agent, binder, and lubricant
- Plasticizer in rubber and polymer processing
- Mold release agent in rubber and plastics
- Food & Packaging (Limited Use)
- May be used in food-contact materials (subject to regulatory approval)
- Not typically used as a direct food additive
- Pharmaceuticals
- As a reagent in drug manufacturing and lab synthesis
- Cleaning and Descaling Agents
- Used in descalers, cleaning solutions, and household products
Safety & Handling:
- Toxicity: Low toxicity; generally recognized as safe (GRAS) for pharmaceutical use
- Irritation: Minimal risk; can cause mild irritation in bulk handling
- Storage: Store in tightly closed containers in a cool, dry place
- Shelf Life: Stable under normal conditions; avoid high heat and moisture
Packaging: Drum